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AMT-253 is a potential first-in-class MUC18-directed ADC with a proprietary linker-payload design   AMT-253 demonstrated a manageable safety profile, consistent with other TOP1-inhibitor based ADCs Promising antitumor activity was observed in heavily pretreated patients with melanoma and gynecologic cancers without MUC18 preselection SHANGHAI, Oct. 19, 2025 /PRNewswire/ — Multitude Therapeutics, Inc., a clinical stage biopharmaceutical company focused on the development of ADC drugs, today announced interim results from its ongoing Phase I/II open-label, multicenter dose escalation and expansion study evaluating AMT-253, a MUC18-directed antibody-drug-conjugate (ADC), in patients with melanoma and other advanced solid tumors. The data are being presented on October…

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The Ohio State Buckeyes are the best team in America, and it’s not close.It’s not just that Julian Sayin is completing 80% of his passes, or that the projected WR1s in the next two NFL Drafts — Carnell Tate and Jeremiah Smith — are shredding secondaries. It’s that Matt Patricia’s defense has allowed just 41 total points through seven games.In a week when three top-25 teams lost to unranked opponents — and with only one unbeaten team remaining in each of the Power 4 conferences — the Buckeyes have never looked more like favorites to repeat as national champions.Still, even…

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Is Brian Kelly worth it?With LSU sitting at 5-2 after a stunning loss to No. 17 Vanderbilt — the Tigers’ first defeat to the Commodores since 1990 — head coach Brian Kelly’s job security is once again under the microscope. Brian Kelly has gone 46-35 at LSU over three-and-half years as the Tigers head coach. (Photo by Carly Mackler/Getty Images) According to USA TODAY Sports’ annual database of college coaches’ salaries, Kelly is the eighth-highest paid coach in college football, earning $10.175 million in 2025. Only three SEC coaches — Georgia’s Kirby Smart, Texas’ Steve Sarkisian, and Alabama’s Kalen DeBoer…

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Underscores MorseLife’s exceptional workplace culture and enduring commitment to purpose-driven senior care WEST PALM BEACH, Fla., Oct. 18, 2025 /PRNewswire/ — MorseLife, a nationally recognized, award-winning leader in senior care, has been named to the 2025 Fortune Best Workplaces in Aging Services in the Small / Medium Senior Housing category. This marks the fourth consecutive year that MorseLife has received this recognition, a testament to its strong workplace culture and commitment to offering a thriving, innovative, and healthy work environment. Keith Myers, Chief Executive Officer of MorseLife, said, “We are incredibly proud to once again be recognized as one of…

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